About Us

Our Story

The idea for Synple started back in 2015. At the time most of us were still working in the Bode group at ETH, where we had just launched the SnAP reagents commercially. We were getting a lot of feedback about how powerful the SnAP method was but it was clear that some people were uncomfortable handling the tin and that there was some variability in the results depending on how experienced the chemist was with SnAP chemistry and what their source of reagents was. During one of our meetings we discussed how great it would be if we could encapsulate all the reagents needed for the reaction and then have an automated machine in which one could simply add the cartridge and press go. Thus our “coffee machine for chemistry” concept was born.

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Benedikt started the development of the machine during the last year of his PhD and as a small team we worked to develop the optimized reaction sequences and reagent cartridges that would enable the machine to carry out not only the reaction but also the work-up and purification in a fully automated manner. Following development of the basic proof of concept, we founded Synple Chem and subsequently secured seed investment that enabled us to produce and test a beta version of our technology with customers across pharma, biotechs, CROs and academia.

Since completion of the pilot phase we have launched a new version of the machine and have added many more reaction class to the technologies capabilities. Today we have customers across Europe, the US and Asia and we continue, as a relatively small team, to develop new reaction classes and expand the applicability of the machine. Our goal is to provide easy to use, safe, efficiency-enhancing organic synthesis solutions to accelerate discovery research

Early working protoypes

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Meet the Synple Chem Team

Dr. Benedikt Wanner
Dr. Benedikt Wanner
Co-Founder & CEO

wanner@synplechem.com

Benedikt graduated from ETH Zurich in the group of Professor Bode and has started developing this idea during the time as a PhD student. For this business idea he was awarded with the ETH pioneer fellowship for the development of the idea into a viable product.
Dr. Paula Nichols
Dr. Paula Nichols
Co-Founder & CCO

nichols@synplechem.com

In addition to almost a decade’s experience as a medicinal chemist at major pharmaceutical companies (GlaxoSmithKline, Eisai Pharmaceuticals), where she was involved with all aspects of drug discovery, particularly the remodeling of hit compounds to provide candidates suitable for clinical trials, Paula brings experience of technology commercialization and experience of working in international cross-functional teams and managing external research and commercialization partners.
Dr. Vijaya Pattabiraman
Dr. Vijaya Pattabiraman
Co-Founder & Research Manager

pattabiraman@synplechem.com

Vijaya brings expertise in the areas of synthetic chemistry and biomolecular chemistry. He has performed research in four different countries, both in academia and industry for over 10 years. He has extensive experience in scientific management, project negotiations and in managing outsourced & collaborative project teams.
Dr. Tuo Jiang
Dr. Tuo Jiang
Co-Founder - Head of R&D

jiang@synplechem.com

Tuo obtained his PhD degree from Prof. Jan-E. Bäckvall's group at Stockholm University, Sweden. He has more than 10 years experience in synthetic chemistry from four research laboratories in Asia and Europe. He has been the lead chemist on this technology and knows it inside out.
Prof. Jeffrey Bode
Prof. Jeffrey Bode
Scientific Advisor ETH Zürich

bode@synplechem.com

Prof. Bode is one of the leading experts in organic chemistry and has won numerous awards. He maintains his own research group as a professor at the ETH Zurich with his group of 30 young scientists. Both his knowledge in chemistry and his experience with industry collaborations and consulting make him an essential part.
Prof. Anastasios Polyzos
Prof. Anastasios Polyzos
Scientific Advisor University Melbourne

polyzos@synplechem.com

Prof. Polyzos is a synthetic organic chemist with a world-recognized expertise in Flow Chemistry. Following a post-doctoral fellowship with Prof. Steven V. Ley at the University of Cambridge, he was appointed to Senior Lecturer at the University of Melbourne with a co-appointment to Australia’s national research agency, CSIRO, where he leads the flow chemistry and catalysis laboratory.

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