Why Synple?

Easy Access to Novel Molecules

Synple Chem provides new automated synthesizers using revolutionary reagent capsules to make the synthesis of molecules faster and more efficient.

The plug & play system can be self-installed in under one hour and training on the system typically takes less than 10 minutes. Simply add the starting material and scan the cartridge to load the pre-optimized methods and prepare the system for the reaction. No programming or optimization necessary!
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Benefits

The combination of our small, easy to use, automated synthesizer with the reagent cartridges and pre-optimized methods, offers genuine “off-the-shelf” solutions for chemical reactions, thus minimizing both time spent on reaction optimization and waste generated.

The hands-on time for a reaction is only 5 minutes, rather than several hours, which can be required for some traditional reactions, work-ups and purifications. This not only frees up the user to concentrate on other activities but also significantly reduces labor costs.

The system also offers safety benefits since all the reagents are contained either within the cartridge or the system itself, thus minimizing exposure to toxic materials and simplifying waste disposal.

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Is the Synple 2 the right tool for you?

As chemists ourselves, we have all had past experiences of new technologies that promise greatness but for one reason or another end up gathering dust and taking up space in the fume hood. We recognize that with new technologies, always comes a certain degree of uncertainty and you may find yourself questioning if this is the right tool.

Is this the right tool for me?
Will I use it often enough?
Is it worth the investment?

Try Now - Risk Free!

Equipment Purchase

100% satisfaction guarantee
reduced price cartridges

Pay Per Use

no capital investment
build credit with each cartridge purchase
 

Therefore, it is important to us that you take your time in establishing the impact of our automated cartridge-based chemistry. We want you to be confident in the technology and what it can do for you. This is why we have tailored our purchasing models to support your initial assessment of the technology.

Accessing the technology

With three different ways of accessing the technology and flexible options to switch between the them, you can experience for yourself the advantages of the technology, at very little cost or risk to yourself and the company. We even offer contract synthesis options for those companies with restricted capacity for wet chemistry. Get in touch today to discuss your opportunity to benefit from the technology. There’s so little to lose but everything to gain!

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Time and Cost Saving

In addition to the safety and reproducibility advantages of the system, the time-saving benefits of our technology mean that labor costs are significantly reduced.

For labor intensive reactions, such as the N-heterocycle formation, investment in the machine pays off after only 60 reactions!

Even for the relatively simple reactions, like reductive aminations, you will soon be reaping the rewards!

Cost comparison of Snyple and Batch work

The table shows a detailed comparison of time, cost and reproducibility to run a Heterocycle forming (SnAP) reaction automatically on the Synple platform and manually in the a standard batch reaction setup.
 
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The table shows a detailed comparison of time, cost and reproducibility to run a reductive amination automatically on the Synple platform and manually in the a standard batch reaction setup.
 
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The table shows a detailed comparison of time, cost and reproducibility to run a PROTAC formation reaction automatically on the Synple platform and manually in the a standard batch reaction setup.
 
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Shape the Future

It is clear that chemistry automation will be increasingly important in the future. Through the use of our technology, you have the opportunity to also help shape the the direction of the technology.

We operate in a highly collaborative manner to develop new applications of interest to our customers. As a user, you will have the chance to request new reaction classes, influence the methodologies, and have free access to our prototype cartridges for testing in-house on your own projects.