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Capex Model

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N-Heterocycle Formation Cartridges

H001 - Morpholine

H002 - Oxazepane

H004 - 2-Methylmorpholine

H005 - Piperazine

H006 - Diazepane

H007 - 3-Methylmorpholine

H010 - Morpholine-2-spiro-(3-Pyr)

H011 - Morpholine-2-spiro-(4-Pip)

H090 - 9-OMe-Benzoxazepane

H091 - 7-Br-9-OMe-Benzoxazepane

Reductive Amination Cartridges

R001 - Reductive Amination

PROTAC Formation Cartridges

P001 - CRBN-PEG1

P002 - CRBN-PEG2

P003 - CRBN-PEG3

P004 - CRBN-PEG4

P005 - CRBN-PEG5

P001L - CRBN-PEG1

P002L - CRBN-PEG2

P003L - CRBN-PEG3

P004L - CRBN-PEG4

P005L - CRBN-PEG5

P021 - VHL-PEG1

P022 - VHL-PEG2

P023 - VHL-PEG3

P024 - VHL-PEG4

P025 - VHL-PEG5

Biotin tag cartridges

BT002 - Biotin tag-PEG2-NH2

BT003 - Biotin tag-PEG3-NH2

BT004 - Biotin tag-PEG4-NH2

BT022 - Biotin tag-PEG2-a-COOTfp

BT023 - Biotin tag-PEG3-a-COOTfp

BT024 - Biotin tag-PEG4-a-COOTfp

BT032 - Biotin tag-PEG2-COOTfp

BT033 - Biotin tag-PEG3-COOTfp

BT034 - Biotin tag-PEG4-COOTfp

Mitsunobu

M001 - Mitsunobu

Amide Formation

A011 - Amide Formation

Deoxyfluorination

F001 - Deoxyfluorination

Azide Formation

A001 - Azide Formation

Protection group chemistry

B001 - Boc protection 0.5 mmol

B002 - Boc protection 1.2 mmol

B011 - Boc deprotection

B021 - Silyl deprotection

B031 - Cbz protection

B032 - Nosyl protection

Suzuki coupling

C001 - Suzuki DPP-Pd

C002 - Suzuki Pd/Al2O3

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